44IB
Crystal structure of human glutaminyl cyclase in complex with Inhibitor LL1260
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutaminyl-peptide cyclotransferase | polymer | 329 | 37557.4 | 1 | UniProt (Q16769) | Homo sapiens (human) | Glutaminyl cyclase,QC,sQC,Glutaminyl-tRNA cyclotransferase,Glutamyl cyclase,EC |
| 2 | B (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) PubChem (3777159) | |||
| 3 | C (A) | ~{N}-[2-(5-methylimidazol-1-yl)ethyl]-4-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrimidin-2-amine | non-polymer | 425.4 | 1 | Chemie (A1FDO) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 6 | F, G, H, I, J (A) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) PubChem (888) | |||
| 7 | K (A) | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37557.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 826.6 | |
| All* | Total formula weight | 38384.0 |
