44HP
Drosophila AHR PAS-B (M284C/Y336L)-ARNT PAS-B heterodimer bound to alpha-naphthoflavone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Ahr homolog spineless | polymer | 120 | 13733.6 | 2 | UniProt (O61543) | Drosophila melanogaster (fruit fly) | |
| 2 | B, D (B, D) | Aryl hydrocarbon receptor nuclear translocator | polymer | 107 | 12623.3 | 2 | UniProt (P53762) | Mus musculus (house mouse) | ARNT protein,Dioxin receptor,nuclear translocator,Hypoxia-inducible factor 1-beta,HIF-1-beta,HIF1-beta |
| 3 | E, I (A, C) | 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | non-polymer | 272.3 | 2 | Chemie (BHF) PubChem (11790) | |||
| 4 | F, J (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 5 | G, H, K (A, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, C: 264 - 381 (UniProt: O61543)
B, D: 360 - 464 (UniProt: P53762)
| PDB | External Database | Details |
|---|---|---|
| Gly 262 | - | expression tag |
| Ser 263 | - | expression tag |
| Cys 284 | Met 284 | engineered mutation |
| Leu 336 | Tyr 336 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 358 | - | expression tag |
| Ser 359 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52713.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 963.6 | |
| All* | Total formula weight | 53677.4 |
