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43SN

Alpha-7 nicotinic acetylcholine receptor bound to inhibitory bicyclic peptide KP1877 in a resting state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G, I
(A, C, E, G, I)
Neuronal acetylcholine receptor subunit alpha-7polymer50256505.25UniProt (P36544)Homo sapiens (human)nAChR7,Nicotinic acetylcholine receptor subunit alpha-7
2B, D, F, H, J
(B, D, F, H, J)
synthetic peptide KP1877polymer171658.95synthetic construct
3K, L, M, N, O...
(K, L, M, N, O...)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.410In PDB
GlyTouCan (G42666HT)
4U, V, W, X, Y
(A, C, E, G, I)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.25Chemie (NAG)
PubChem (24139)
5AA, BA, CA, DA, Z
(D, F, H, J, B)
waterwater18.05Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight290820.4
BranchedNumber of molecules10
Total formula weight4244.0
Non-Polymers*Number of molecules5
Total formula weight1106.0
All*Total formula weight296170.5
*Water molecules are not included.

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PDB entries from 2026-08-26

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