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43IB

Cryo-EM structure of canonical human nucleosome.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Histone H3.1polymer13615437.22UniProt (P68431)
Pfam (PF00125)
Homo sapiens (human)Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2B, F
(B, F)
Histone H4polymer10311394.42UniProt (P62805)
Pfam (PF15511)
Homo sapiens (human)
3C, G
(C, G)
Histone H2A type 2-Apolymer13014125.52UniProt (Q6FI13)
Pfam (PF00125)
Pfam (PF16211)
Homo sapiens (human)H2A-clustered histone 18,H2A-clustered histone 19,Histone H2A.2,Histone H2A/o
4D, H
(D, H)
Histone H2B type 1-C/E/F/G/Ipolymer12613937.22UniProt (P62807)
Pfam (PF00125)
Homo sapiens (human)Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l
5I
(I)
DNA (136-MER)polymer558171477.81synthetic construct
6J
(J)
DNA (136-MER)polymer558173243.81synthetic construct
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight454510.4
All*Total formula weight454510.4
*Water molecules are not included.

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PDB entries from 2026-09-30

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