3ZZN
5-Mutant (R79W, R151A, E279A, E299A,E313A) Lactate-Dehydrogenase from Thermus thermophillus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | LACTATE DEHYDROGENASE | polymer | 310 | 32599.4 | 4 | UniProt (Q5SJA1) Pfam (PF00056) Pfam (PF02866) In PDB | THERMUS THERMOPHILUS | |
| 2 | A, D | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 22 - 331 (UniProt: Q5SJA1)
| PDB | External Database | Details |
|---|---|---|
| Trp 79 | Arg 58 | engineered mutation |
| Ala 151 | Arg 128 | engineered mutation |
| Ala 279 | Glu 260 | engineered mutation |
| Ala 299 | Glu 279 | engineered mutation |
| Ala 313 | Glu 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130397.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 854.4 | |
| All* | Total formula weight | 131251.9 |
