3ZXO
CRYSTAL STRUCTURE OF THE MUTANT ATP-BINDING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | REDOX SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS | polymer | 129 | 13716.8 | 2 | UniProt (P95194) Pfam (PF02518) UniProt (by SIFTS) (P9WGK3) In PDB | MYCOBACTERIUM TUBERCULOSIS | TWO COMPONENT SENSOR HISTIDINE KINASE DEVS |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A, B: 454 - 578 (UniProt: P95194)
| PDB | External Database | Details |
|---|---|---|
| Gly 450 | - | expression tag |
| Ala 451 | - | expression tag |
| Mse 452 | - | expression tag |
| Val 453 | - | expression tag |
| Ala 509 | Lys 509 | engineered mutation |
| Mse 534 | Leu 534 | engineered mutation |
| Mse 562 | Val 562 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27433.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 459.1 | |
| All* | Total formula weight | 27892.7 |
