3ZXI

Crystal structure of human mitochondrial tyrosyl-tRNA synthetase in complex with a tyrosyl-adenylate analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	TYROSYL-TRNA SYNTHETASE, MITOCHONDRIAL	polymer	356	39962.4	2	UniProt (Q9Y2Z4) Pfam (PF00579)	HOMO SAPIENS (HUMAN)	TYROSINE--TRNA LIGASE, TYRRS
2	C, D (A, B)	PHOSPHORIC ACID 2-AMINO-3-(4-HYDROXY-PHENYL)-PROPYL ESTER ADENOSIN-5'YL ESTER	non-polymer		495.4	2	Chemie (TYA)

Sequence modifications

A, B: 32 - 375 (UniProt: Q9Y2Z4)

PDB	External Database	Details
Met 28	-	expression tag
Arg 29	-	expression tag
Gly 30	-	expression tag
Ser 31	-	expression tag
Arg 376	-	expression tag
Ser 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79924.7
Non-Polymers*	Number of molecules	2
	Total formula weight	990.8
All*	Total formula weight	80915.5

*Water molecules are not included.