Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

3ZWT

Structure of Human Dihydroorotate Dehydrogenase with a Bound Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIALpolymer36739856.51UniProt (Q02127)
Pfam (PF01180)
HOMO SAPIENS (HUMAN)DIHYDROOROTATE DEHYDROGENASE, DHODEHASE, DIHYDROOROTATE OXIDASE
2B
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3C
(A)
OROTIC ACIDnon-polymer156.11Chemie (ORO)
4D, E
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
5F
(A)
2-{[(2,5-DICHLOROPHENYL)METHYL]SULFANYL}-5-ETHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-OLnon-polymer355.21Chemie (KFZ)
6G, H
(A)
ACETATE IONnon-polymer59.02Chemie (ACT)
7I
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
8J
(A)
waterwater18.0216Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39856.5
Non-Polymers*Number of molecules8
Total formula weight1313.3
All*Total formula weight41169.9
*Water molecules are not included.

238268

PDB entries from 2025-07-02

PDB statisticsPDBj update infoContact PDBjnumon