3ZWT
Structure of Human Dihydroorotate Dehydrogenase with a Bound Inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL | polymer | 367 | 39856.5 | 1 | UniProt (Q02127) Pfam (PF01180) | HOMO SAPIENS (HUMAN) | DIHYDROOROTATE DEHYDROGENASE, DHODEHASE, DIHYDROOROTATE OXIDASE |
2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
3 | C (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
4 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
5 | F (A) | 2-{[(2,5-DICHLOROPHENYL)METHYL]SULFANYL}-5-ETHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-OL | non-polymer | 355.2 | 1 | Chemie (KFZ) | |||
6 | G, H (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
7 | I (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
8 | J (A) | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39856.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1313.3 | |
All* | Total formula weight | 41169.9 |