3ZSG
X-ray structure of p38alpha bound to TAK-715
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | MITOGEN-ACTIVATED PROTEIN KINASE 14 | polymer | 362 | 41494.3 | 1 | UniProt (Q16539) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | MAP KINASE 14, MAPK 14, CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG-BINDING PROTEIN, CSAID-BINDING PROTEIN, CSBP, MAP KINASE MXI2, MAX-INTERACTING PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA, MAP KINASE P38 ALPHA, SAPK2A, P38A |
| 2 | A | TAK-715 | non-polymer | 399.5 | 1 | Chemie (T75) | |||
| 3 | A | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
| 4 | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence modifications
A: 2 - 360 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41494.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 691.9 | |
| All* | Total formula weight | 42186.2 |
