3ZO3
The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA | polymer | 351 | 40917.6 | 1 | UniProt (P00517) Pfam (PF00069) | BOS TAURUS (BOVINE) | PKA C-ALPHA |
| 2 | B (I) | CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA | polymer | 20 | 2226.4 | 1 | UniProt (Q3SX13) | BOS TAURUS | PKI-ALPHA |
| 3 | C (A) | 6-(2,9-DIAZASPIRO[5.5]UNDECAN-2-YL)-9H-PURINE | non-polymer | 272.3 | 1 | Chemie (QNI) | |||
| 4 | D, E, F, G, H... (A) | METHANOL | non-polymer | 32.0 | 7 | Chemie (MOH) | |||
| 5 | J, K, L, M (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | O, P (A, I) | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43144.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 865.0 | |
| All* | Total formula weight | 44009.0 |
