3ZO1
The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA | polymer | 351 | 40917.6 | 1 | UniProt (P00517) Pfam (PF00069) | BOS TAURUS (BOVINE) | PKA C-ALPHA |
| 2 | B (I) | CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA | polymer | 18 | 1973.2 | 1 | UniProt (Q3SX13) | BOS TAURUS | PKI-ALPHA |
| 3 | C (A) | 6-(1,9-DIAZASPIRO[5.5]UNDECAN-9-YL)-9H-PURINE | non-polymer | 272.3 | 1 | Chemie (SIJ) | |||
| 4 | D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | H, I (A) | METHANOL | non-polymer | 32.0 | 2 | Chemie (MOH) | |||
| 6 | J, K (A, I) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42890.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 704.8 | |
| All* | Total formula weight | 43595.6 |
