3ZMQ
Src-derived mutant peptide inhibitor complex of PTP1B
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 | polymer | 329 | 38447.8 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | HOMO SAPIENS (HUMAN) | PROTEIN-TYROSINE PHOSPHATASE 1B, PTP-1B |
2 | C | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | polymer | 10 | 1262.2 | 1 | UniProt (P12931) In PDB | HOMO SAPIENS | PROTO-ONCOGENE C-SRC, PP60C-SRC, P60-SRC |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
C: 1 - 10 (UniProt: P12931)
PDB | External Database | Details |
---|---|---|
Met -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Ser 215 | Cys 215 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 2 | Pro 528 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 39710.0 | |
All* | Total formula weight | 39710.0 |