3ZM9
The mechanism of allosteric coupling in choline kinase a1 revealed by a rationally designed inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CHOLINE KINASE ALPHA | polymer | 383 | 44954.5 | 2 | UniProt (P35790) Pfam (PF01633) | HOMO SAPIENS (HUMAN) | CK, CHETK-ALPHA, ETHANOLAMINE KINASE, EK, CK, CHETK-ALPHA, ETHANOLAMINE KINASE, EK, CHOLINE KINASE A1 |
| 2 | C, D (A, B) | 1-(4-(4-(4-((6-amino-9H-purin-9-yl)methyl)phenyl)butyl)benzyl)-4- (dimethylamino)pyridinium | non-polymer | 492.6 | 2 | Chemie (QMQ) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89908.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 985.3 | |
| All* | Total formula weight | 90894.2 |
