3ZM5
CRYSTAL STRUCTURE OF MURF LIGASE IN COMPLEX WITH CYANOTHIOPHENE INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE | polymer | 465 | 51630.4 | 1 | UniProt (Q8DNV6) Pfam (PF01225) Pfam (PF08245) Pfam (PF02875) | STREPTOCOCCUS PNEUMONIAE R6 | MURF LIGASE |
| 2 | B (A) | 2,4-bis(chloranyl)-N-[3-cyano-6-[(4-hydroxyphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl]-5-morpholin-4-ylsulfonyl-benzamide | non-polymer | 607.5 | 1 | Chemie (IGM) | |||
| 3 | C (A) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A: 1 - 457 (UniProt: Q8DNV6)
| PDB | External Database | Details |
|---|---|---|
| Arg 458 | - | expression tag |
| Ser 459 | - | expression tag |
| His 460 | - | expression tag |
| His 461 | - | expression tag |
| His 462 | - | expression tag |
| His 463 | - | expression tag |
| His 464 | - | expression tag |
| His 465 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51630.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 607.5 | |
| All* | Total formula weight | 52237.9 |
