3ZGL
Crystal structures of Escherichia coli IspH in complex with AMBPP a potent inhibitor of the methylerythritol phosphate pathway
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE | polymer | 332 | 36639.5 | 2 | UniProt (P62623) Pfam (PF02401) In PDB | ESCHERICHIA COLI | ISPH, (E)-4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE (E)-4-AMINO-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE |
2 | A, B | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) | |||
3 | A, B | (2E)-4-amino-3-methylbut-2-en-1-yl trihydrogen diphosphate | non-polymer | 261.1 | 2 | Chemie (10E) | |||
4 | water | water | 18.0 | 809 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 316 (UniProt: P62623)
PDB | External Database | Details |
---|---|---|
Met -15 | - | expression tag |
Arg -14 | - | expression tag |
Gly -13 | - | expression tag |
Ser -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
Gly -5 | - | expression tag |
Ser -4 | - | expression tag |
Ala -3 | - | expression tag |
Cys -2 | - | expression tag |
Glu -1 | - | expression tag |
Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 73279.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1225.5 | |
All* | Total formula weight | 74504.5 |