3ZGD
crystal structure of a KEAP1 mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 | polymer | 310 | 33840.8 | 2 | UniProt (Q14145) Pfam (PF01344) In PDB | HOMO SAPIENS (HUMAN) | CYTOSOLIC INHIBITOR OF NRF2, INRF2, KELCH-LIKE PROTEIN 19 |
2 | A, B | ACETATE ION | non-polymer | 59.0 | 10 | Chemie (ACT) | |||
3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
4 | water | water | 18.0 | 667 | Chemie (HOH) |
Sequence modifications
A, B: 321 - 609 (UniProt: Q14145)
PDB | External Database | Details |
---|---|---|
Met 300 | - | expression tag |
Gly 301 | - | expression tag |
Ser 302 | - | expression tag |
Ser 303 | - | expression tag |
His 304 | - | expression tag |
His 305 | - | expression tag |
His 306 | - | expression tag |
His 307 | - | expression tag |
His 308 | - | expression tag |
His 309 | - | expression tag |
Ser 310 | - | expression tag |
Ser 311 | - | expression tag |
Gly 312 | - | expression tag |
Leu 313 | - | expression tag |
Val 314 | - | expression tag |
Pro 315 | - | expression tag |
Arg 316 | - | expression tag |
Gly 317 | - | expression tag |
Ser 318 | - | expression tag |
His 319 | - | expression tag |
Met 320 | - | expression tag |
Ala 540 | Glu 540 | engineered mutation |
Ala 542 | Glu 542 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 67681.7 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 613.4 | |
All* | Total formula weight | 68295.1 |