3ZG0
Crystal structure of ceftaroline acyl-PBP2a from MRSA with non- covalently bound ceftaroline and muramic acid at allosteric site obtained by cocrystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PENICILLIN BINDING PROTEIN 2 PRIME | polymer | 642 | 73286.7 | 2 | UniProt (Q54113) Pfam (PF05223) Pfam (PF03717) Pfam (PF00905) UniProt (by SIFTS) (A0A0H3JPA5) | STAPHYLOCOCCUS AUREUS SUBSP. AUREUS MU50 | PENICILLIN-BINDING PROTEIN 2A |
| 2 | C, L (A, B) | Ceftaroline, bound form | non-polymer | 607.7 | 2 | Chemie (AI8) | |||
| 3 | D, E, F, G, M... (A, B) | CADMIUM ION | non-polymer | 112.4 | 8 | Chemie (CD) | |||
| 4 | H, I, Q, R (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | J, S (A, B) | Ceftaroline | non-polymer | 605.7 | 2 | Chemie (1W8) | |||
| 6 | K, T (A, B) | beta-muramic acid | non-polymer | 251.2 | 2 | Chemie (MUR) | |||
| 7 | U, V (A, B) | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 146573.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3970.5 | |
| All* | Total formula weight | 150543.8 |
