3ZFW

Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	KINESIN LIGHT CHAIN 2	polymer	263	29861.9	2	UniProt (Q91YS4) Pfam (PF13424) Pfam (PF00515) Pfam (PF13374) UniProt (by SIFTS) (O88448) In PDB	MUS MUSCULUS (HOUSE MOUSE)	KLC 2
2	X, Y	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2	polymer	45	4716.0	2	UniProt (Q8IWE5) In PDB	HOMO SAPIENS (HUMAN)	PH DOMAIN-CONTAINING FAMILY M MEMBER 2, SALMONELLA-INDUCED FILAMENTS A AND KINESIN-INTERACTING PROTEIN, SIFA AND KINESIN-INTERACTING PROTEIN

Sequence modifications

X, Y: 203 - 212 (UniProt: Q8IWE5)

PDB	External Database	Details
Met 182	-	expression tag
Gly 183	-	expression tag
Ser 184	-	expression tag
Ser 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
Ser 192	-	expression tag
Ser 193	-	expression tag
Gly 194	-	expression tag
Leu 195	-	expression tag
Val 196	-	expression tag
Pro 197	-	expression tag
Arg 198	-	expression tag
Gly 199	-	expression tag
Ser 200	-	expression tag
His 201	-	expression tag
Met 202	-	expression tag
Thr 213	-	expression tag
Gly 214	-	expression tag
Ser 215	-	expression tag
Thr 216	-	expression tag
Gly 217	-	expression tag
Ser 218	-	expression tag
Thr 219	-	expression tag
Gly 220	-	expression tag
Ser 221	-	expression tag
Thr 222	-	expression tag
Gly 223	-	expression tag
Ser 224	-	expression tag
His 225	-	expression tag
Met 226	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	69155.9
All*	Total formula weight	69155.9

*Water molecules are not included.