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3X3F

TRAIL-R2 Extracellular Region Complexed to a Fab fragment from Human Agonist Antibody KMTR2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Heavy chain of KMTR2polymer22924899.81Homo sapiens
2B
(L)
Light chain of KMTR2polymer21423350.91Homo sapiens
3C
(A)
Tumor necrosis factor receptor superfamily member 10Bpolymer14215975.81UniProt (O14763)
Pfam (PF00020)
Homo sapiens (human)Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2
4D
(H)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
5E
(H)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6F, G, H, I, J
(L)
GLYCEROLnon-polymer92.15Chemie (GOL)
7K, L, M
(H, L, A)
waterwater18.0276Chemie (HOH)
Sequence modifications
A: 54 - 184 (UniProt: O14763)
PDBExternal DatabaseDetails
Val 67Ala 67SEE REMARK 999
Ser 185-expression tag
Arg 186-expression tag
Ala 187-expression tag
Asp 188-expression tag
Tyr 189-expression tag
Lys 190-expression tag
Asp 191-expression tag
Asp 192-expression tag
Asp 193-expression tag
Asp 194-expression tag
Lys 195-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight64226.4
Non-Polymers*Number of molecules7
Total formula weight717.1
All*Total formula weight64943.6
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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