3X3F
TRAIL-R2 Extracellular Region Complexed to a Fab fragment from Human Agonist Antibody KMTR2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | Heavy chain of KMTR2 | polymer | 229 | 24899.8 | 1 | Homo sapiens | ||
| 2 | L | Light chain of KMTR2 | polymer | 214 | 23350.9 | 1 | Homo sapiens | ||
| 3 | A | Tumor necrosis factor receptor superfamily member 10B | polymer | 142 | 15975.8 | 1 | UniProt (O14763) Pfam (PF00020) In PDB | Homo sapiens (human) | Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2 |
| 4 | H | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | H | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | L | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence modifications
A: 54 - 184 (UniProt: O14763)
| PDB | External Database | Details |
|---|---|---|
| Val 67 | Ala 67 | SEE REMARK 999 |
| Ser 185 | - | expression tag |
| Arg 186 | - | expression tag |
| Ala 187 | - | expression tag |
| Asp 188 | - | expression tag |
| Tyr 189 | - | expression tag |
| Lys 190 | - | expression tag |
| Asp 191 | - | expression tag |
| Asp 192 | - | expression tag |
| Asp 193 | - | expression tag |
| Asp 194 | - | expression tag |
| Lys 195 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 64226.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 717.1 | |
| All* | Total formula weight | 64943.6 |
