3X0C
Crystal structure of PIP4KIIBETA I368A complex with GMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | polymer | 393 | 44886.8 | 2 | UniProt (P78356) Pfam (PF01504) | Homo sapiens (human) | 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta, Diphosphoinositide kinase 2-beta, Phosphatidylinositol 5-phosphate 4-kinase type II beta, PI(5)P 4-kinase type II beta, PIP4KII-beta, PtdIns(5)P-4-kinase isoform 2-beta |
| 2 | C, D, E, F (A, B) | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 4 | Chemie (5GP) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A, B: 31 - 416 (UniProt: P78356)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Asn 26 | - | expression tag |
| Cys 27 | - | expression tag |
| Ala 28 | - | expression tag |
| Pro 29 | - | expression tag |
| Gly 30 | - | expression tag |
| Ala 368 | Ile 368 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89773.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1452.9 | |
| All* | Total formula weight | 91226.5 |
