3WUW

KIR3DL1 in complex with HLA-B*57:01.I80T

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HLA class I histocompatibility antigen, B-57 alpha chain	polymer	275	31627.0	1	UniProt (P18465) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889)	Homo sapiens (human)	Bw-57, MHC class I antigen B*57
2	B (B)	Beta-2-microglobulin	polymer	98	11635.0	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)	Beta-2-microglobulin form pI 5.3
3	C (C)	Peptide	polymer	9	966.1	1	UniProt (by SIFTS) (P01834)	HOMO SAPIENS
4	D (G)	Killer cell immunoglobulin-like receptor 3DL1	polymer	301	33513.8	1	UniProt (P43629) Pfam (PF00047)	Homo sapiens (human)	CD158 antigen-like family member E, HLA-BW4-specific inhibitory NK cell receptor, MHC class I NK cell receptor, Natural killer-associated transcript 3, NKAT-3, p70 natural killer cell receptor clones CL-2/CL-11, p70 NK receptor CL-2/CL-11
5	E, F, G (G)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	H, I, J, K (A, B, C, G)	water	water		18.0	493	Chemie (HOH)

Sequence modifications

A: 1 - 275 (UniProt: P18465)

PDB	External Database	Details
Thr 80	Ile 104	engineered mutation

G: 7 - 292 (UniProt: P43629)

PDB	External Database	Details
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
Asp 2	-	expression tag
Asp 3	-	expression tag
Asp 4	-	expression tag
Asp 5	-	expression tag
Lys 6	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77741.9
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	78405.6

*Water molecules are not included.