3WU1
Crystal structure of the ETS1-RUNX1-DNA ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Runt-related transcription factor 1 | polymer | 123 | 13540.4 | 1 | UniProt (Q03347) Pfam (PF00853) | Mus musculus (mouse) | Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit |
| 2 | B (B) | Protein C-ets-1 | polymer | 109 | 12970.8 | 1 | UniProt (P14921) Pfam (PF00178) | Homo sapiens (human) | p54 |
| 3 | C (C) | DNA (5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3') | polymer | 16 | 4843.2 | 1 | |||
| 4 | D (D) | DNA (5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3') | polymer | 16 | 4954.2 | 1 | |||
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 36308.6 | |
| All* | Total formula weight | 36308.6 |
