3WSR
Crystal structure of CLEC-2 in complex with O-glycosylated podoplanin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | C-type lectin domain family 1 member B | polymer | 128 | 15157.0 | 2 | UniProt (Q9P126) Pfam (PF00059) In PDB | Homo sapiens (human) | C-type lectin-like receptor 2, CLEC-2 |
| 2 | C, D | Peptide from Podoplanin | polymer | 18 | 1703.8 | 2 | UniProt (Q86YL7) In PDB | Homo sapiens | |
| 3 | E, F | beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-alpha-D-galactopyranose | branched | 674.6 | 2 | In PDB GlyTouCan (G56682BC) | |||
| 4 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, B: 96 - 221 (UniProt: Q9P126)
C, D: 38 - 54 (UniProt: Q86YL7)
| PDB | External Database | Details |
|---|---|---|
| Gly 94 | - | expression tag |
| Ser 95 | - | expression tag |
| Ser 99 | Cys 99 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Cys 55 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 33721.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1349.2 | |
| All* | Total formula weight | 35071.0 |
