3WQ9
Crystal structure of Hsp90-alpha N-terminal domain in complex with 2-(4-Hydroxy-cyclohexylamino)-4-[5-(4-phenyl-imidazol-1-yl)-isoquinolin-1-yl]-benzamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock protein HSP 90-alpha | polymer | 237 | 26739.9 | 1 | UniProt (P07900) Pfam (PF13589) | Homo sapiens (human) | Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38 |
| 2 | B (A) | 2-[(trans-4-hydroxycyclohexyl)amino]-4-[5-(4-phenyl-1H-imidazol-1-yl)isoquinolin-1-yl]benzamide | non-polymer | 503.6 | 1 | Chemie (YUK) | |||
| 3 | C (A) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A: 1 - 236 (UniProt: P07900)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26739.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 503.6 | |
| All* | Total formula weight | 27243.5 |
