3WPD
Crystal structure of horse TLR9 in complex with inhibitory DNA4084
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Toll-like receptor 9 | polymer | 802 | 89427.6 | 1 | UniProt (Q2EEY0) Pfam (PF13516) Pfam (PF00560) Pfam (PF13855) Pfam (PF18837) | Equus caballus (horse) | |
| 2 | B (C) | DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*G)-3') | polymer | 10 | 3101.0 | 1 | synthetic | ||
| 3 | C (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | G, H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | I (A) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 26 - 817 (UniProt: Q2EEY0)
| PDB | External Database | Details |
|---|---|---|
| Arg 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Pro 24 | - | expression tag |
| Trp 25 | - | expression tag |
| Glu 818 | - | expression tag |
| Phe 819 | - | expression tag |
| Leu 820 | - | expression tag |
| Val 821 | - | expression tag |
| Pro 822 | - | expression tag |
| Arg 823 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92528.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 730.6 | |
| All* | Total formula weight | 93683.6 |
