3WLW
Molecular Architecture of the ErbB2 Extracellular Domain Homodimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor tyrosine-protein kinase erbB-2 | polymer | 564 | 62190.5 | 2 | UniProt (P04626) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) | Homo sapiens (human) | Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2 |
| 2 | C, E (H, C) | Antibody H Chain | polymer | 217 | 23148.8 | 2 | Homo sapiens | ||
| 3 | D, F (L, D) | Antibody L Chain | polymer | 217 | 23085.4 | 2 | Homo sapiens | ||
| 4 | G (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | H (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | I, J, K, L, M... (A, B, H, L, C...) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 216849.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 217494.9 |
