3WKE

Crystal structure of soluble epoxide hydrolase in complex with t-AUCB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Bifunctional epoxide hydrolase 2	polymer	561	63514.5	1	UniProt (P34913) Pfam (PF00702) Pfam (PF00561) In PDB	Homo sapiens (human)	Cytosolic epoxide hydrolase 2, CEH, Epoxide hydratase, Soluble epoxide hydrolase, SEH, Lipid-phosphate phosphatase
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4	A	4-[(trans-4-{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylcarbamoyl]amino}cyclohexyl)oxy]benzoic acid	non-polymer		412.5	1	Chemie (AUB)
5		water	water		18.0	81	Chemie (HOH)

Sequence modifications

A: 1 - 555 (UniProt: P34913)

PDB	External Database	Details
His 556	-	expression tag
His 557	-	expression tag
His 558	-	expression tag
His 559	-	expression tag
His 560	-	expression tag
His 561	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63514.5
Non-Polymers*	Number of molecules	3
	Total formula weight	531.8
All*	Total formula weight	64046.3

*Water molecules are not included.