3WKA
Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bifunctional epoxide hydrolase 2 | polymer | 561 | 63514.5 | 1 | UniProt (P34913) Pfam (PF00702) Pfam (PF00561) In PDB | Homo sapiens (human) | Cytosolic epoxide hydrolase 2, CEH, Epoxide hydratase, Soluble epoxide hydrolase, SEH, Lipid-phosphate phosphatase |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | A | 6-amino-1-methyl-5-(piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione | non-polymer | 224.3 | 1 | Chemie (S0G) | |||
5 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 1 - 555 (UniProt: P34913)
PDB | External Database | Details |
---|---|---|
His 556 | - | expression tag |
His 557 | - | expression tag |
His 558 | - | expression tag |
His 559 | - | expression tag |
His 560 | - | expression tag |
His 561 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 63514.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 343.5 | |
All* | Total formula weight | 63858.0 |