3WGX
Crystal structure of ERp46 Trx2 in a complex with Prx4 C-term
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thioredoxin domain-containing protein 5 | polymer | 113 | 12975.6 | 2 | UniProt (Q8NBS9) Pfam (PF00085) | Homo sapiens (human) | ERp46, Endoplasmic reticulum resident protein 46, ER protein 46, Thioredoxin-like protein p46 |
| 2 | C, D (C, D) | Peroxiredoxin-4 | polymer | 20 | 2092.3 | 2 | UniProt (O08807) Pfam (PF10417) | Mus musculus | Prx4 |
| 3 | E (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 388 | Chemie (HOH) |
Sequence modifications
A, B: 190 - 298 (UniProt: Q8NBS9)
| PDB | External Database | Details |
|---|---|---|
| Gly 186 | - | expression tag |
| Ser 187 | - | expression tag |
| His 188 | - | expression tag |
| Met 189 | - | expression tag |
| Ala 220 | Cys 220 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 30135.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 30228.0 |
