3WDZ

Crystal Structure of Keap1 in Complex with phosphorylated p62

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Kelch-like ECH-associated protein 1	polymer	311	34270.1	1	UniProt (Q9Z2X8) Pfam (PF01344)	Mus musculus (mouse)	Cytosolic inhibitor of Nrf2, INrf2
2	B (B)	Peptide from Sequestosome-1	polymer	14	1611.6	1	UniProt (Q64337)	Mus musculus	STONE14, Ubiquitin-binding protein p62
3	C (A)	water	water		18.0	5	Chemie (HOH)

Sequence modifications

A: 321 - 609 (UniProt: Q9Z2X8)

PDB	External Database	Details
Met 299	-	expression tag
Gly 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
Asp 307	-	expression tag
Tyr 308	-	expression tag
Asp 309	-	expression tag
Ile 310	-	expression tag
Pro 311	-	expression tag
Thr 312	-	expression tag
Thr 313	-	expression tag
Glu 314	-	expression tag
Asn 315	-	expression tag
Leu 316	-	expression tag
Tyr 317	-	expression tag
Phe 318	-	expression tag
Gln 319	-	expression tag
Gly 320	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35881.7
All*	Total formula weight	35881.7

*Water molecules are not included.