3WDD

Mutant N-terminal domain of Mycobacterium tuberculosis ClpC1, F2Y, bound to Cyclomarin A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Probable ATP-dependent Clp protease ATP-binding subunit	polymer	153	17089.6	1	UniProt (P0A522) Pfam (PF02861) UniProt (by SIFTS) (P9WPC9)	Mycobacterium tuberculosis	ClpC1
2	B (B)	Cyclomarin A	polymer	7	1063.3	1	BIRD (PRD_001124)	Streptomyces
3	C (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
4	D, E (A, B)	water	water		18.0	168	Chemie (HOH)

Sequence modifications

A: 1 - 145 (UniProt: P0A522)

PDB	External Database	Details
Tyr 2	Phe 2	engineered mutation
Leu 146	-	expression tag
Glu 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	18152.9
Non-Polymers*	Number of molecules	1
	Total formula weight	59.0
All*	Total formula weight	18211.9

*Water molecules are not included.