3WD9

Crystal structure of phosphodiesterase 4B in complex with compound 10f

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	polymer	377	43352.7	2	UniProt (Q07343) Pfam (PF00233)	Homo sapiens (human)	DPDE4, PDE32
2	C, F (A, B)	4-[(4-{2-[(2,2-dimethylpropyl)amino]-2-oxoethyl}phenyl)amino]-2-phenylpyrimidine-5-carboxamide	non-polymer		417.5	2	Chemie (QPC)
3	D, G (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	E, H (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
5	I, J (A, B)	water	water		18.0	341	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86705.3
Non-Polymers*	Number of molecules	6
	Total formula weight	1046.0
All*	Total formula weight	87751.3

*Water molecules are not included.