3WD5
Crystal structure of TNFalpha in complex with Adalimumab Fab fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tumor necrosis factor | polymer | 157 | 17328.6 | 1 | UniProt (P01375) Pfam (PF00229) | Homo sapiens (human) | TNFalpha |
| 2 | B (L) | Adalimumab Light Chain | polymer | 213 | 23332.9 | 1 | Homo sapiens (human) | ||
| 3 | C (H) | Adalimumab Heavy Chain | polymer | 219 | 23273.9 | 1 | Homo sapiens (human) | ||
| 4 | D, E, F (A, L, H) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A: 1 - 157 (UniProt: P01375)
| PDB | External Database | Details |
|---|---|---|
| Asp 31 | Arg 107 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 63935.4 | |
| All* | Total formula weight | 63935.4 |
