3WCV

The structure of a deoxygenated 400 kda hemoglobin provides a more accurate description of the cooperative mechanism of giant hemoglobins: CA bound form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	A1 globin chain of giant V2 hemoglobin	polymer	146	16368.7	2	UniProt (S0BBU7) Pfam (PF00042)	Lamellibrachia satsuma (Hydrothermal vent tubeworm)
2	B, F (B, F)	A2 globin chain of giant V2 hemoglobin	polymer	144	15951.9	2	UniProt (S0BBR6) Pfam (PF00042)	Lamellibrachia satsuma (Hydrothermal vent tubeworm)
3	C, G (C, G)	B2 globin chain of giant V2 hemoglobin	polymer	150	16519.5	2	UniProt (S0BCU7) Pfam (PF00042)	Lamellibrachia satsuma (Hydrothermal vent tubeworm)
4	D, H (D, H)	B1 globin chain of giant V2 hemoglobin	polymer	149	16228.6	2	UniProt (S0BAP9) Pfam (PF00042)	Lamellibrachia satsuma (Hydrothermal vent tubeworm)
5	I, J (I, J)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	2	In PDB GlyTouCan (G64181RO)
6	CA, EA, K, N, R... (G, H, A, B, C...)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	8	Chemie (HEM)
7	DA, FA, L, O, S... (G, H, A, B, C...)	OXYGEN MOLECULE	non-polymer		32.0	8	Chemie (OXY)
8	AA, BA, M, P, Q... (F, A, B)	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
9	GA, HA, IA, JA, KA... (A, B, C, D, E...)	water	water		18.0	59	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	130137.6
Branched	Number of molecules	2
	Total formula weight	2113.9
Non-Polymers*	Number of molecules	22
	Total formula weight	5428.4
All*	Total formula weight	137679.9

*Water molecules are not included.