3W9J
Structural basis for the inhibition of bacterial multidrug exporters
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Multidrug resistance protein MexB | polymer | 1052 | 113706.0 | 6 | UniProt (P52002) Pfam (PF00873) In PDB | Pseudomonas aeruginosa | Multidrug-efflux transporter MexB |
2 | A, B, C, D, E... | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 15 | Chemie (LMT) | |||
3 | B, E | [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | non-polymer | 693.8 | 2 | Chemie (P9D) |
Sequence modifications
A, B, C, D, E, F: 1 - 1046 (UniProt: P52002)
PDB | External Database | Details |
---|---|---|
His 1047 | - | expression tag |
His 1048 | - | expression tag |
His 1049 | - | expression tag |
His 1050 | - | expression tag |
His 1051 | - | expression tag |
His 1052 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 682236.0 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 9046.8 | |
All* | Total formula weight | 691282.8 |