3W96

Crystal Structure of Human Nucleosome Core Particle lacking H2A N-terminal region

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3.1	polymer	139	15719.4	2	UniProt (P68431) Pfam (PF00125) In PDB	Homo sapiens (human)	Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l
2	B, F	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511) In PDB	Homo sapiens (human)
3	C, G	Histone H2A type 1-B/E	polymer	124	13588.9	2	UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB	Homo sapiens (human)	Histone H2A.2, Histone H2A/a, Histone H2A/m
4	D, H	Histone H2B type 1-J	polymer	129	14217.5	2	UniProt (P06899) Pfam (PF00125) In PDB	Homo sapiens (human)	Histone H2B.1, Histone H2B.r, H2B/r
5	I, J	146-mer DNA	polymer	146	45053.9	2
6	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7	E, I	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)

Sequence modifications

A, E: 0 - 135 (UniProt: P68431)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

B, F: 0 - 102 (UniProt: P62805)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

C, G: 10 - 129 (UniProt: P04908)

PDB	External Database	Details
Gly 6	-	expression tag
Ser 7	-	expression tag
His 8	-	expression tag
Met 9	-	expression tag

D, H: 0 - 125 (UniProt: P06899)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	200512.8
Non-Polymers*	Number of molecules	3
	Total formula weight	145.3
All*	Total formula weight	200658.1

*Water molecules are not included.