3W87
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with SH-1-103
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dihydroorotate dehydrogenase (fumarate) | polymer | 314 | 34154.3 | 2 | UniProt (Q4D3W2) Pfam (PF01180) In PDB | Trypanosoma cruzi | DHOD, DHODase, DHOdehase, Dihydroorotate oxidase |
| 2 | A, B | 5-{4-[5-(methoxycarbonyl)naphthalen-2-yl]butyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | non-polymer | 396.4 | 2 | Chemie (W87) | |||
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 25 | Chemie (GOL) | |||
| 4 | A, B | CACODYLATE ION | non-polymer | 137.0 | 4 | Chemie (CAC) | |||
| 5 | B, A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) | |||
| 6 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 24 | Chemie (EDO) | |||
| 7 | A, B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 8 | A | COBALT HEXAMMINE(III) | non-polymer | 161.1 | 2 | Chemie (NCO) | |||
| 9 | water | water | 18.0 | 821 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 312 (UniProt: Q4D3W2)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68308.6 | |
| Non-Polymers* | Number of molecules | 62 |
| Total formula weight | 6686.0 | |
| All* | Total formula weight | 74994.6 |
