3W7R
Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 390 | 42636.4 | 1 | UniProt (Q02127) Pfam (PF01180) In PDB | Homo sapiens (human) | DHOdehase, Dihydroorotate oxidase |
2 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
3 | A | DECYLAMINE-N,N-DIMETHYL-N-OXIDE | non-polymer | 201.3 | 6 | Chemie (DDQ) | |||
4 | A | 2,6-dioxo-5-[2-(4-phenylphenyl)ethyl]-1,2,3,6- tetrahydropyrimidine-4-carboxylic acid | non-polymer | 336.3 | 1 | Chemie (W7A) | |||
5 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 22 | Chemie (GOL) | |||
7 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
8 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
9 | A | ACETATE ION | non-polymer | 59.0 | 7 | Chemie (ACT) | |||
10 | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
PDB | External Database | Details |
---|---|---|
Met 7 | - | expression tag |
Gly 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
His 14 | - | expression tag |
His 15 | - | expression tag |
His 16 | - | expression tag |
His 17 | - | expression tag |
His 18 | - | expression tag |
Ser 19 | - | expression tag |
Ser 20 | - | expression tag |
Gly 21 | - | expression tag |
His 22 | - | expression tag |
Ile 23 | - | expression tag |
Asp 24 | - | expression tag |
Asp 25 | - | expression tag |
Asp 26 | - | expression tag |
Asp 27 | - | expression tag |
Lys 28 | - | expression tag |
His 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42636.4 | |
Non-Polymers* | Number of molecules | 43 |
Total formula weight | 5016.0 | |
All* | Total formula weight | 47652.4 |