3W7F

Crystal structure of the C(30) carotenoid dehydrosqualene synthase from staphylococcus aureus complexed with farnesyl thiopyrophosphate

Replaces:  2ZCP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Dehydrosqualene synthase	polymer	293	34787.5	2	UniProt (A9JQL9) Pfam (PF00494) In PDB	Staphylococcus aureus	4,4'-diapophytoene synthase, DAP synthase, Diapophytoene synthase
2	A, B	S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE	non-polymer		398.4	4	Chemie (FPS)
3	A, B	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4		water	water		18.0	354	Chemie (HOH)

Sequence modifications

A, B: 1 - 287 (UniProt: A9JQL9)

PDB	External Database	Details
Ala -5	-	expression tag
Ala -4	-	expression tag
Ala -3	-	expression tag
Ala -2	-	expression tag
Ala -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69575.0
Non-Polymers*	Number of molecules	10
	Total formula weight	1739.4
All*	Total formula weight	71314.4

*Water molecules are not included.