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3W7E

Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-5-179

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Dihydroorotate dehydrogenase (fumarate)polymer31334067.22UniProt (Q4D3W2)
Pfam (PF01180)
Trypanosoma cruziDHOD, DHODase, DHOdehase, Dihydroorotate oxidase
2C, Q
(A, B)
5-[2-(7-methoxynaphthalen-1-yl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acidnon-polymer340.32Chemie (W7F)
3AA, D, E, F, G...
(B, A)
GLYCEROLnon-polymer92.121Chemie (GOL)
4BA, O
(B, A)
FLAVIN MONONUCLEOTIDEnon-polymer456.32Chemie (FMN)
5P
(A)
COBALT HEXAMMINE(III)non-polymer161.11Chemie (NCO)
6CA, DA
(A, B)
waterwater18.0677Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68134.5
Non-Polymers*Number of molecules26
Total formula weight3688.4
All*Total formula weight71822.9
*Water molecules are not included.

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PDB entries from 2025-12-17

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