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3W75

Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-149

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Dihydroorotate dehydrogenase (fumarate)polymer31334067.22UniProt (Q4D3W2)
Pfam (PF01180)
Trypanosoma cruziDHOD, DHODase, DHOdehase, Dihydroorotate oxidase
2C, M
(A, B)
5-[2-(3,5-dimethoxyphenyl)ethyl]-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acidnon-polymer320.32Chemie (W75)
3D, E, F, G, H...
(A, B)
GLYCEROLnon-polymer92.115Chemie (GOL)
4L, U
(A, B)
FLAVIN MONONUCLEOTIDEnon-polymer456.32Chemie (FMN)
5V
(B)
COBALT HEXAMMINE(III)non-polymer161.11Chemie (NCO)
6W, X
(A, B)
waterwater18.0706Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68134.5
Non-Polymers*Number of molecules20
Total formula weight3095.8
All*Total formula weight71230.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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