3W5E
Crystal structure of phosphodiesterase 4B in complex with compound 31e
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | polymer | 377 | 43352.7 | 2 | UniProt (Q07343) Pfam (PF00233) | Homo sapiens (human) | DPDE4, PDE32 |
| 2 | C, F (A, B) | N-tert-butyl-2-{4-[(5,5-dioxido-2-phenyl-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl)amino]phenyl}acetamide | non-polymer | 464.6 | 2 | Chemie (NVW) | |||
| 3 | D, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, H (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 340 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86705.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1140.1 | |
| All* | Total formula weight | 87845.4 |
