3W2C
Structure of Aurora kinase A complexed to benzoimidazole-indazole inhibitor XV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, E, G) | Aurora kinase A | polymer | 261 | 30308.8 | 4 | UniProt (O14965) Pfam (PF00069) | Homo sapiens (human) | Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, hARK1, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A |
| 2 | E, F, G, H (A, C, E, G) | 2-{4-[3-(1H-benzimidazol-2-yl)-1H-indazol-6-yl]-1H-pyrazol-1-yl}-N-(3-methylbutyl)acetamide | non-polymer | 427.5 | 4 | Chemie (N15) | |||
| 3 | I, J, K, L (A, C, E, G) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 121235.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1710.0 | |
| All* | Total formula weight | 122945.3 |
