3VZB
Crystal structure of Sphingosine Kinase 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Sphingosine kinase 1 | polymer | 360 | 39860.4 | 3 | UniProt (Q9NYA1) Pfam (PF00781) | Homo sapiens (human) | SK 1, SPK 1 |
| 2 | D, L (A, B) | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol | non-polymer | 299.5 | 2 | Chemie (SQS) PubChem (1104) PubChem (31270) PubChem (444299) PubChem (447699) PubChem (54453873) PubChem (56610175) PubChem (57351389) PubChem (5326412) PubChem (5353955) PubChem (5496506) PubChem (6604741) PubChem (10086129) PubChem (11130338) PubChem (12359052) PubChem (12359053) PubChem (12359056) PubChem (5280335) PubChem (123484476) | |||
| 3 | E, M, S (A, B, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F, G, H, I, J... (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 15 | Chemie (EDO) | |||
| 5 | X, Y, Z (A, B, C) | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence modifications
A, B, C: 9 - 364 (UniProt: Q9NYA1)
| PDB | External Database | Details |
|---|---|---|
| Ala 5 | - | expression tag |
| Met 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Ser 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 119581.3 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1818.2 | |
| All* | Total formula weight | 121399.5 |
