3VZB
Crystal structure of Sphingosine Kinase 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Sphingosine kinase 1 | polymer | 360 | 39860.4 | 3 | UniProt (Q9NYA1) Pfam (PF00781) | Homo sapiens (human) | SK 1, SPK 1 |
| 2 | D, L (A, B) | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol | non-polymer | 299.5 | 2 | Chemie (SQS) | |||
| 3 | E, M, S (A, B, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F, G, H, I, J... (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 15 | Chemie (EDO) | |||
| 5 | X, Y, Z (A, B, C) | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence modifications
A, B, C: 9 - 364 (UniProt: Q9NYA1)
| PDB | External Database | Details |
|---|---|---|
| Ala 5 | - | expression tag |
| Met 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Ser 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 119581.3 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1818.2 | |
| All* | Total formula weight | 121399.5 |
