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3VYQ

Crystal structure of the methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence in space group P1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, D)
Methyl-CpG-binding domain protein 4polymer748332.62UniProt (Q9Z2D7)
Pfam (PF01429)
Mus musculus (mouse)Methyl-CpG-binding protein MBD4, Mismatch-specific DNA N-glycosylase
2B
(B)
DNA (5'-D(*AP*CP*AP*TP*CP*(5CM)P*GP*GP*TP*GP*A)-3')polymer113372.21
3C
(C)
DNA (5'-D(*TP*CP*AP*CP*TP*GP*GP*AP*TP*GP*T)-3')polymer113364.21
4E, G, H
(A, D)
ZINC IONnon-polymer65.43Chemie (ZN)
5F
(B)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
6I, J, K, L
(A, B, C, D)
waterwater18.055Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight23401.6
Non-Polymers*Number of molecules4
Total formula weight258.3
All*Total formula weight23659.9
*Water molecules are not included.

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PDB entries from 2025-10-01

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