3VX4

Crystal Structure of the Nucleotide-Binding Domain of S. mutans ComA, a Bifunctional ATP-binding Cassette Transporter Involved in the Quorum-sensing Pathway

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, D)	Putative ABC transporter, ATP-binding protein ComA	polymer	273	30349.4	2	UniProt (Q8DW05) Pfam (PF00005)	Streptococcus mutans
2	C, E (A, D)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
3	D, F (A, D)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	G, H (A, D)	water	water		18.0	148	Chemie (HOH)

Sequence modifications

A, D: 495 - 760 (UniProt: Q8DW05)

PDB	External Database	Details
Met 494	-	expression tag
Ala 690	Glu 690	engineered mutation
His 761	-	expression tag
His 762	-	expression tag
His 763	-	expression tag
His 764	-	expression tag
His 765	-	expression tag
His 766	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	60698.9
Non-Polymers*	Number of molecules	4
	Total formula weight	1063.0
All*	Total formula weight	61761.9

*Water molecules are not included.