3VWK

Ternary crystal structure of the human NKT TCR-CD1d-4'deoxy-alpha-galactosylceramide complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Antigen-presenting glycoprotein CD1d	polymer	284	32324.4	1	UniProt (P15813) Pfam (PF16497) Pfam (PF07654) In PDB	Homo sapiens (human)	R3G1
2	B	Beta-2-microglobulin	polymer	99	11748.2	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (human)	Beta-2-microglobulin form pI 5.3
3	C	NKT15 T cell receptor alpha-chain	polymer	209	23227.7	1		Homo sapiens
4	D	NKT15 T cell receptor beta-chain	polymer	246	28033.2	1		Homo sapiens
5	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	A	N-{(2S,3R)-1-[(4-deoxy-alpha-D-xylo-hexopyranosyl)oxy]-3-hydroxyoctadecan-2-yl}hexacosanamide	non-polymer		826.3	1	Chemie (4GH)
7	D	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
8		water	water		18.0	20	Chemie (HOH)

Sequence modifications

A: 3 - 277 (UniProt: P15813)

PDB	External Database	Details
Ser 0	-	expression tag
Pro 1	-	expression tag
Gly 2	-	expression tag
His 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	95333.4
Non-Polymers*	Number of molecules	4
	Total formula weight	1293.0
All*	Total formula weight	96626.4

*Water molecules are not included.