3VSQ
Crystal Structure of the Cytoplasmic Domain of G-Protein-Gated Inward Rectifier Potassium Channel Kir3.2 E236R Mutant in the presence of ethanol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G protein-activated inward rectifier potassium channel 2 | polymer | 208 | 23777.1 | 1 | UniProt (Q8C4T8) Pfam (PF17655) UniProt (by SIFTS) (P48542) | Mus musculus (mouse) | GIRK-2, Inward rectifier K(+) channel Kir3.2, Potassium channel, inwardly rectifying subfamily J member 6 |
| 2 | B, C (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 3 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | E (A) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
A: 53 - 74 (UniProt: Q8C4T8)
A: 200 - 381 (UniProt: Q8C4T8)
| PDB | External Database | Details |
|---|---|---|
| Gly 49 | - | expression tag |
| Ser 50 | - | expression tag |
| His 51 | - | expression tag |
| Met 52 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Arg 236 | Glu 236 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23777.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 180.6 | |
| All* | Total formula weight | 23957.6 |
