3VRM
Structure of cytochrome P450 Vdh mutant T107A with bound vitamin D3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Vitamin D(3) 25-hydroxylase | polymer | 411 | 45457.6 | 1 | UniProt (C4B644) Pfam (PF00067) In PDB | Pseudonocardia autotrophica (Amycolata autotrophica) | Cytochrome P450 |
| 2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | A | (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL | non-polymer | 384.6 | 1 | Chemie (VD3) | |||
| 4 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A: 1 - 403 (UniProt: C4B644)
| PDB | External Database | Details |
|---|---|---|
| Ala 107 | Thr 107 | engineered mutation |
| Leu 404 | - | expression tag |
| Glu 405 | - | expression tag |
| His 406 | - | expression tag |
| His 407 | - | expression tag |
| His 408 | - | expression tag |
| His 409 | - | expression tag |
| His 410 | - | expression tag |
| His 411 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45457.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1001.1 | |
| All* | Total formula weight | 46458.7 |
