3VQD
HIV-1 IN core domain in complex with 5-methyl-3-phenyl-1,2-oxazole-4-carboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | POL polyprotein | polymer | 158 | 17248.5 | 2 | UniProt (Q72498) Pfam (PF00665) | Human immunodeficiency virus 1 | |
| 2 | C, D, G, H (A, B) | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
| 3 | E, I (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | F (A) | 5-methyl-3-phenyl-1,2-oxazole-4-carboxylic acid | non-polymer | 203.2 | 1 | Chemie (MOK) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A, B: 55 - 212 (UniProt: Q72498)
| PDB | External Database | Details |
|---|---|---|
| Ser 56 | Cys 771 | engineered mutation |
| Asp 131 | Trp 846 | engineered mutation |
| Asp 139 | Phe 854 | engineered mutation |
| His 185 | Phe 900 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34497.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 845.0 | |
| All* | Total formula weight | 35342.0 |
